Since the advent of a lens system that enabled the visualization of bacteria and protists in 1671, the microscope remains a ubiquitous tool for the scientific study of live and fixed microorganisms. Investigating the structure, function, and typing of the highly diverse array of microorganisms spans heterogeneous applications including, but not limited to, the elucidation, diagnosis, and treatment of human and plant disease, food and water safety testing, vaccine development, investigation and production of industrial lipases, protein transfection to mammalian cells, environmental health and impact appraisal, horticultural and agricultural soil assessment, and exploration of alternative fuel sources.
This varied application base requires imaging instruments compatible with a variety of objective magnifications, dry and oil resolving power, multiple imaging channels, and advanced image analysis capabilities, features demonstrated on BioTek imagers using a number of microbial models. In addition to automated microscopy features, BioTek cell imaging multi-mode readers increase selection from a broader range of assays available to the field of microbiology via absorbance, fluorescence, luminescence, fluorescence polarization, time resolved fluorescence, and Alpha detection capabilities. Other options, such as shaking, temperature, robotic, and microfluidic perfusion control available with some Cytation™ and Lionheart™ configurations, provide even more versatility to increase choice, throughput, and design efficacy in microbiology assay workflows.
BioTek’s Visual Abstracts are brief animated presentations describing the Augmented Microscopy workflow of a specific application.
- Automated Scoring of Acid-fast Bacteria (AFB) by Fluorescent Smear Microscopy
- Quantitative Image Analysis of Bacilli Viability in Agar Mounted Soil Samples
- Automated Image Analysis of Dictydium Sporothecae Biovolume Using Robotics
- Image Analysis of Herpesvirales Specificity Challenge using Direct Fluorescence Antibody Assay (DFA)
- Monitoring Viral Infection of Mammalian Cells using Digital Fluorescence Microscopy
- Monitoring Saccharomyces cerevisiea Growth with Brightfield Microscopy in Real Time
Infographic: How to Calculate Cell Count/Volume Using Automated Label Free Image Analysis
- Lionheart FX Automated Microscope
- Lionheart LX Automated Microscope
- Cytation 5 Cell Imaging Multi-Mode Reader
- Cytation 1 Cell Imaging Multi-Mode Reader
- BioStack Microplate Stacker
Learn more about Microbiology applications - search our Application Notes and technical documentation in Resources.