BioTek: Microplate Instrumentation & Software Solutions
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Technical Resources

Technical resources are available to illustrate product specific capabilities and common applications for BioTek microplate instrumentation. These documents assist with both the operation of BioTek instrumentation to achieve peak performance, and their implementation in common experimental design.

 
 


Drug Discovery & Development

2009 Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity
2009 Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds
2009 A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology
2008 The EL406™ Microplate Washer Dispenser Combines Thorough Washing and Precise Dispensing in One Space-Saving Instrument Configuration
2006 NanoQuot™, A Cost-Effective, Flexible Nanoliter Dispenser for High Throughput Screening
2006 Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery
2005 Using BioTek’s ELx405™ Microplate Washer to Automate Washing of the QuantiGene® Reagent System
2003 Fully Automated Sample Preparation and Nanoelectrospray MS Analysis Using ZipTips, the Precision 2000 and the NanoMate 100

ISSX

2009 Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity
2009 Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds

International Poultry Expo

2010 Versatile, Cost-effective Automation of Avian Influenza and Mycoplasma Gallisepticum-Synoviae ELISAs

LabAutomation

2010 Versatile, Cost-effective Automation of Avian Influenza and Mycoplasma Gallisepticum-Synoviae ELISAs
2010 Utility of Hybrid Multi-Mode Readers using Both Monochromator- and Filter-Based Detection Capabilities as Demonstrated with FP, TR-FRET, and Fluorescence Intensity Assays for the Measurement of ADP Accumulation
2010 Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds
2010 Automated Cytotoxicity Profiling Using the EL406 Washer Dispenser with CELLestial™ Assay Kits for Microplates
2010 Automated Cell Dispensing into 1536-Well Microplates for HTS Screening
2010 Automated Washing of Magnetic Bead xMAP Assays for Multiplexed mRNA and Metabolic Hormone Assays
2010 Automated Processing of a Homogeneous phospho-ERK1/2 Assay for Use as a Generic GPCR Sensor
2010 A Novel Homogeneous, Fluorescence-based Technology for Dual Measure of Phosphodiesterases and Their Downstream Effector Kinase Activities in Biochemical and Cell-based Assays
2010 Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled Receptor Using A Novel 3-D Cell Culture Technique
2009 Automated Triplex Assay to Assess Cell Viability, Cytotoxicity and Apoptosis
2009 Optimizing Robustness of the Membrane-free, Oris™ Cell Migration Assay for High Throughput Screening using the BioTek Synergy™ HT Multi-Mode Microplate Reader
2009 Novel Gyrasol Sensor Assay Platform with the Hybrid Technology™ Multi-Mode Reader Synergy™ 4
2009 Automated ELISA Liquid Handling with EL406 Combination Microplate Washer Dispenser
2009 Invitrogen's Predictor™ hERG Fluorescence Polarization Assay Using BioTek's Synergy™ 4 Multi-Mode Microplate Reader with Hybrid Technology™
2009 Volume Scaling of the Transcreener® ADP2 FP Assay on the BioTek Synergy™ 2 and 4 Multi-Mode Microplate Readers Allows For Easy Transition From Assay Development to High-Throughput Screening
2008 Validation of a Suite of Invitrogen Assay Technologies on BioTek Instruments
2008 Fluorescence Intensity, FRET, and TR-FRET Homogeneous Assay Technologies from Invitrogen™ Validated on BioTek’s new Versatile Hybrid Microplate Reader, Synergy™ 4
2006 NanoQuot™, A Cost-Effective, Flexible Nanoliter Dispenser for High Throughput Screening
2006 Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery
2004 Using BioTek’s ELx405™ Select CW Microplate Washer to Wash Loosely Adherent Tissue Culture Cells
2004 MicroFill: A 96-/384-Well Microplate Reagent Dispenser for HTS and Drug Discovery
2004 Applications of an Automated Microplate Stacking Device for HTS and Multi-Instrument Interface
2004 The ELx405 384-Well Microplate Washer: Designed to Meet the Rigors of Biomolecular Screening
2003 Synergy HT: A Unique Multi-Detection Microplate Reader for HTS and Drug Discovery
2000 Using BioTek’s Precision 2000 Automated Pipetting System for Microarray Sample Preparation

Laboratory Robotics Interest Group

2009 Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity
2009 Low Volume Nucleic Acid Quantification using A Multi-Volume Microplate Spectrophotometer System
2009 Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds
2009 A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology
2009 Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery
2005 Synergy™ HT: A Multi-Mode Microplate Reader for Today's High Performance Luminescence Research

MipTec

2009 A Cost-Effective Workflow for High-Throughput Screening of G Protein-Coupled Receptors (GPCR)
2009 Automation of a Luminescent Assay to measure UDP-glucuronosyltransferase (UGT) Enzyme Activity
2009 Automation of a Multiplexed Cell-based Assay to Measure Simultaneously Inhibition and Induction of the Cytochrome P450 Isoform 3A4 by Small Molecule Compounds
2009 A Simple and Robust Automated Kinase Profiling Platform using Luminescent ADP Accumulation Technology
2009 Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery
2004 Automating a Lowry Protein Assay with BioTek's Precision™ XS Microplate Sample Processor

Other

2010 Automated Multiplexed Cell-Based Cytochrome P450 Assays

Pittcon

2010 Analytical Performance of a Multi-Volume Microplate Accessory for Microplate Spectrophotometer Platforms

Planet xMAP

2010 Critical Automated Washer Parameters for Optimal Washing and Bead Recovery of MagPlex and MicroPlex Microspheres
2009 Automated Washing of Magnetic Bead xMAP Assays for Multiplexed mRNA and Metabolic Hormone Assays

Society Of Toxicology

2010 Cytotoxicity Profiling of The Anticancer Agent Thiostrepton

Society for Biomolecular Sciences

2010 Automated Triplexed Hepatocyte-Based Viability and CYP1A and CYP3A Induction Assays in 96- and 384-well Microplates
2010 Homogeneous Cell-based Signal Transduction Assays
2010 Quencher Dyes Can Alter the Pharmacokinetic Response Profiles of Living Cells in Fluorescence-based Calcium Mobilization Assays
2010 Novel Fluorescence-Based Microplate Assay for Screening Inhibitors of Thioredoxin and Protein Disulfi de Isomerase
2010 Development of a Live-Cell Based Reactive Oxygen Species (ROS) Assay for use in High-Content Screening of Drug Candidates Using The BioTek Synergy Mx Microplate Reader
2010 Cytotoxicity Profiling of The Anticancer Agent Thiostrepton
2010 Automation of a Microplate Cell-based Assay to Measure Activity of the Histamine H1 G-protein-coupled Receptor Using A Novel 3-D Cell Culture Technique
2009 BacMam-Enabled Cellular Assays Measuring Histone Posttranslational Modifications
2009 Automation of Predictor™ hERG Fluorescence Polarization Assay using Precision™ Automated Pipetting System for Serial Dilution of Small Molecule Drugs for IC50 Determinations
2009 Optimization and Validation of a high-throughput homogeneous Time-Resolved Fluorescence (HTRF®) assay for inhibitors to Class IA Phosphoinositide 3-kinase isoform activity
2009 Automated ELISA Liquid Handling with EL406 Combination Microplate Washer Dispenser
2009 Automation of Luminescence-based CYP Inhibition Assays using BioTek Instrumentation for use in Drug Discovery
2009 Multiplexed GPCR Assays using HTRF® Technology
2009 Automated ApoTox-Glo Assay to Simultaneously Assess Cell Viability, Cytotoxicity and Apoptosis
2008 The Synergy Family of Readers; A Lower Cost High Performance Alternative for Running AlphaScreen Assays
2007 Using Synergy™ 2 Multi-Mode Microplate Reader to run cAMP and Tumor Necrosis Factor HTRF® assays for High-Throughput Screening
2006 NanoQuot™, A Cost-Effective, Flexible Nanoliter Dispenser for High Throughput Screening
2006 Synergy™ 2 Multi-Mode Microplate Reader: A Novel Approach to Detection for HTS and Drug Discovery
2005 The ELx405™ Microplate Washer: A Family of Washers to Meet the Diverse Needs of Biological Screening
2003 Performance Verification of BioTek's Precision 2000 Using Artel's Multichannel Volume Verification (MVV) System
2000 A Flexible, Multi-Purpose, Multi-Detector HTS Automated Platform